Long-term results of the Coralline Porous Hydroxyapatite HAP-200 as bone implant's biomaterial in Orthopedics and Traumatology

Resumen

A sample of 486 patients implantedwith Porous CoraUine Hydroxyapatite HAP-200 as a bone graft substitute was studied. The period of evolution was from 1 to 6 years. A protocol of clinical investigation was followed in four orthopedic hospitals (three in Cuba and one in Mexico). It allowed standardizing the inclusion approaches, indication of the treatments, surgical procedures, as well as the postoperative evaluation. The pain, inflammation, exhibition of the material, edema and sepsis in the postoperative period was evaluated according to a degree classification from I to III as well as the radiographic aspect of the implants and the general hematological state. According to these indicators a categorization of the general final result was also establishedkeeping in mind the achieved functional restoration. From all of the patients, 26% was considered excellent in the achieved result, 63% was good, 7% fair and 4% poor. The complications were minimum and in no case it was associated in a directly way with the implant biomateriaL By means of longitudinal radiographic studies it was observed that at the time, the implanted biomaterial begins to spread and to
standardize its density with the surrounding bone environment, with the gradual loss of the tissue-implants frontiers. It is also noticed an induced osteogenic, effect and remodeling of the bone structure in areas far from the implanted site. The time of duration of this process depends among other factors on the patient's ageand on the type, place and magnitude of the lesion, what can be interpreted as the assimilation of the biomaterial and its incorporation to the natural dynamics of the bone metabolism.