ESTUDIO COMPARATIVO DE LA BIODISPONIBILIDAD Y FARMACOCINETICA DE UN ENSAYO DE NITROFURANTOINA SUSPENSION

Authors

  • E. Muñoz Laboratorios Técnicos de Medicamentos
  • E. González Laboratorios Técnicos de Medicamentos
  • J. Pérez Instituto de Medicina Tropical "Pedro Kourí"

Abstract

A bioavailability comparative study bet­ween the offlclal suspension on nitrofurantoin, avail­abl-e in the market, and assay of a more stable sus­pention th roungh a eros over test using six heaUy volunteers after taking a standard breakfast was made. lt was demonstrated that relative availability in urine is of 90,8 and 135, 7 % respectively. Sorne pharmacokinetic factors in the testing of the new suspension were assessed. In order to quantify nítro­hlturatoin \n urine an analytic method was adaptad.

Published

2022-10-13

How to Cite

Muñoz, E., González , E., & Pérez, . J. . (2022). ESTUDIO COMPARATIVO DE LA BIODISPONIBILIDAD Y FARMACOCINETICA DE UN ENSAYO DE NITROFURANTOINA SUSPENSION. NATIONAL CENTER FOR SCIENTIFIC RESEARCH (CENIC) CHEMICAL SCIENCES JOURNAL, 18(3), 115-120. Retrieved from https://revista.cnic.cu/index.php/RevQuim/article/view/2057

Issue

Section

Research articles