Degradación intracelular de inmunocomplejo fagocitado por macrófagos

Authors

  • C. Finlay Centro Nacional de Investigaciones Científicas
  • J. Serracent Centro Nacional de Investigaciones Científicas
  • H. Pauste Centro Nacional de Investigaciones Científicas

Abstract

Macrophage culture were supplemented for 72 hours with increasing concentrations of heat inactivated newborn calf serum  (10, 25 and 50%). As expected there was an increase of lysosomal enzyme synthesis related to the concentration of the serum. I immunocomplex was added to culture plates with different concentrations of serum and lysosomal enzyme activities. They phagocytosed and cligested the im­munocomplex at the same rate. These results strongly suggest that the intracellular activity of acid hydrolases is not a factor limiting intra­cellular degradation.

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Published

2022-11-07

How to Cite

Finlay, C., Serracent, J., & Pauste, H. (2022). Degradación intracelular de inmunocomplejo fagocitado por macrófagos. NATIONAL CENTER FOR SCIENTIFIC RESEARCH (CENIC) BIOLOGICAL SCIENCES JOURNAL, 8(3), 001-009. Retrieved from https://revista.cnic.cu/index.php/RevBiol/article/view/2467

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Section

Research articles

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