Serotonin receptores in the isolated atria of Hamster

Authors

  • R. GONZALEZ ALVAREZ Pharmacology Department
  • R. GONZALEZ ALVAREZ Pharmacology Department
  • M. GARCIA RODRIGUEZ Pharmacology Department
  • D. CARVAJAL QUINTANA Pharmacology Department

Abstract

. Since LSD induces a positive chronotropic effect on isolated atria of hamster it is not suitable for characterizing specific serotonin receptors of auricles using cumulative dose-response curves. As isolated atria show neither the so called serotonin receptors M (blocked by morphine) nor nicotinic receptors, the positive chronotropic action of serotonin must relate to some other receptor systems. Serotonin has a transient negative chronotropic action of a cholinergic origin; however neither the direct interaction of indolamine with muscarinic receptors, nor the release of endogenous acetylcholine significantly affect the positive chronotropic action of the agonist on isolated atria

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Published

2022-11-17

How to Cite

GONZALEZ ALVAREZ, R. ., GONZALEZ ALVAREZ, R., GARCIA RODRIGUEZ, . M. ., & CARVAJAL QUINTANA, . D. . (2022). Serotonin receptores in the isolated atria of Hamster . NATIONAL CENTER FOR SCIENTIFIC RESEARCH (CENIC) BIOLOGICAL SCIENCES JOURNAL, 13(2), 273-280. Retrieved from https://revista.cnic.cu/index.php/RevBiol/article/view/2719

Issue

Section

Research articles