Ozonoterapia sistémica e intra-articular en la artritis de la articulación temporomandibular por artritis reumatoide

Abstract

The effects of intra-articular ozone therapy combined with systemic application (rectal route) compared to
intraarticular application along were studied in patients with temporomandibular joint arthritis for rheumatoid arthritis.
Twenty patients were included and divided into two groups of ten each: the first group was treated with intra-articular
ozone therapy (ozone concentration 10 mg/L and a volume of 3 mL), two applications per week during five weeks; the
second group received a combined therapy; intra-articular ozone therapy plus ozone administered by rectal insufflations,
with increasing doses between 30 and 40 mg/L of ozone concentration and 100 and 200 mL (20 applications, one daily). It
was evaluated the width of the cartilage (by ultrasound) at the beginning and the end to the treatment, the clinics symptoms
were evaluated too, such as: pain during mastication, crack and trismus. It was observed a significant decrease of
all these symptoms and also the ultrasound analysis in both groups of patients, but it was achieved more rapidly in the
group treated with the combined therapy. It was concluded that both ways of treatment demonstrated beneficial effects
in the temporomandibular joint arthritis of patients with rheumatoid arthritis, although, the combined therapy was more
efficient, it has not been reported before.