STUDY OF ANTRAL GASTRITIS IN PATIENTS TREATED ULCERATIVES WITH HELICOBACTER PYLORI WITH COLLOIDAL BISMUTH SUBCITRATE (Q-ULCER)

Abstract

Thirty patients (18 females and 12 males) that pre­sented endoscopically peptic ulcer and antral gastritis with Helico­bacter pylori (Hp) were studied. The aim of this study was to know the endoscopy and histological changes of the antral mucous with Hp in ulcerous patients, treated with colloidal bismuth subci­trate (Q-ULCER). Before treatment, 76,6 % of active chronic gas­tritis (ACG) was presented and after treatment as a result a 26,6 % (the percent was diminished). Inactive chronic gastritis was in­creased from 20 to 70 % by tbe histological change in the tissue with loss of neutrophil infiltrate. One patient with ACG before treatment reached the normality. In ali, the Hp clearance was 70 %; tJ1e endoscopy diagnosis presented few variations. It was con­cluded that in the patients where the ACG lost its activity, the heal­ing process of the peptic ulcer and the Hp clearance were superior than the cases that there were no favorable histological changes of the antral mucous and it is importan! to take into account the possi­bility to employ in the future the treatment with Q-ULCER for prevention of che ulcer disease.